Presenting Rodent MDA

In collaboration with the French 3R Center (FC3R), our team-member Corina Berset, Animal Welfare Officer at the University of Zurich, Switzerland, will be talking about MDA in the webinar on "Raffiner l’administration de substances chez les rongeurs". Further details about the event can be found here.

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54. Seminar über Versuchstiere und Tierversuche

Datum: 13. - 14. Mai 2025

Ort: Bundesinstitut für Risikobewertung, Berlin oder Live-Online via Zoom

Format: Hybridveranstaltung

More info here

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Save the Date

for the Swiss 3RCC 3rs Day 2025 taking place in Zurich hosted by the University of Zurich & the ETH Zurich.

FELASA and HSBLAS are glad to invite you to the 16th FELASA Congress, from 2 to 5 June 2025 in Athens, Greece.

After the successful 2022 edition we are excited to host the FELASA 2025 in Athens, Greece, the country where biomedical research was born.

FELASA, the Federation of European Laboratory Animal Science Associations, represents common interests in the furtherance of all aspects of laboratory animal science (LAS) in Europe and beyond. FELASA puts the 3Rs of Laboratory Animal Science ‘Replacement, Reduction, and Refinement’ center stage. FELASA advocates responsible scientific conduct with animals in the life sciences with a particular emphasis on ensuring animal welfare.

Learn more here

Register now!

Second 3Rs Day by i3s in Porto, Portugal (and online) on "Models in Biomedical Research". Find more info here: https://www.i3s.up.pt/event.php?v=327

Don't miss the presentation on rodent MDA by Dr. Paulin Jirkof

By: Dr. Paulin Jirkof (University of Zurich).

Date: September 10, 2024, Helsinki 2 PM EEST

ABSTRACT:

In drug development, a focus on oral formulations aligns with human treatment practices. Preclinical assessments demand crucial oral testing of compounds, often carried out through oral gavage in mice and rats. However, this widely used method lacks accuracy in replicating voluntary substance intake of humans, posing risks of injury and stress to laboratory rodents. This presentation scrutinizes the pros and cons of oral gavage and explores alternative approaches, including uncontrolled oral intake (e.g., via drinking water), and refined, controlled voluntary ingestion protocols. The Micropipette-Guided Drug Administration (MDA) method, employing palatable solutions like sweetened condensed milk diluted with water, will be introduced. The talk will evaluate evidence on the suitability of these alternative methods for administering various experimental substances, such as analgesics, tamoxifen or others, while prioritizing animal welfare.

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Register here

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Karolinska Institutet presents: Webinar with Dr. Paulin Jirkof

Learn more about the pros and cons of oral gavage and explores alternative approaches, including injections, uncontrolled oral intake (e.g., via drinking water), and refined, controlled voluntary ingestion protocols. The Micropipette-Guided Drug Administration (MDA) method, employing palatable solutions like sweetened condensed milk diluted with water, will be introduced. The talk will evaluate evidence on the suitability of these alternative methods for administering various experimental substances, such as analgesics, tamoxifen or others, while prioritizing animal welfare.

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Speaker

Dr. Paulin Jirkof works as the 3R at the University of Zurich's Office for Animal Welfare and 3R. She also chairs the Executive Board of the Swiss 3R Competence Center, is a board member of the Swiss Society for Laboratory Animal Science, and serves as Editor-in-Chief of the journal Laboratory Animal. Her research primarily focuses on refining laboratory rodent practices, with a particular emphasis on assessing and improving animal welfare.

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